Female sex selection using clomiphene citrate and albumin separation of human sperm

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Female sex selection using clomiphene citrate and albumin separation of human sperm.

BACKGROUND This study was undertaken to assess whether the use of clomiphene citrate in conjunction with albumin-separated sperm would alter the sex ratio (expressed as the proportion of males) towards females and, if so, whether this skewing was due solely to the induction of ovulation. METHODS The sex ratios of 184 single and 42 twin births at five assisted reproduction biology clinics were...

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Experiences in Hong Kong with the theory and practice of the albumin column method of sperm separation for sex selection.

Controversy still surrounds the human serum albumin (HSA) method for separation of X- and Y-bearing human spermatozoa. There is doubt about whether the procedure does enrich sperm samples for the chosen sex chromosome. We have applied the HSA separation method in a clinic in Hong Kong, using the method as described by Ericsson et al. [Nature, 246, 421-424 (1973)] taking care to keep the sperm r...

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Clomiphene Citrate and Oocyte Quality

Ovary is a dynamic organ and generates excess amount of reactive oxygen species (ROS) during follicular growth, development, maturation and ovulation [1]. The increased level of ROS is scavenged by antioxidant systems [2]. A moderate increase of ROS could be beneficial for oocyte meiotic maturation and reproductive outcome [3-5]. Overproduction of ROS or depletion of enzymatic antioxidant syste...

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a comparison of clomiphene citrate and sequential clomiphene citrate plus human menopausal gonadotropin for use in conjunction with intrauterine insemination

there are currently ‎many different protocols in use for controlled ovarian hyperstimulation (coh), but the optimal method has ‎not yet been determined. to compare the outcome of coh using ‎clomiphene citrate (cc) versus cc plus human menopausal gonadotropin (hmg) in conjunction with intrauterine insemination (iui), we studied 117 infertile couples‎. iui with cc was used in 92 cycles ‎(group a)...

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CLOMID® (clomiphene citrate tablets USP)

Clomiphene citrate is a white to pale yellow, essentially odorless, crystalline powder. It is freely soluble in methanol; soluble in ethanol; slightly soluble in acetone, water, and chloroform; and insoluble in ether. CLOMID is a mixture of two geometric isomers [cis (zuclomiphene) and trans (enclomiphene)] containing between 30% and 50% of the cis-isomer. Each white scored tablet contains 50 m...

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 2002

ISSN: 1460-2350

DOI: 10.1093/humrep/17.5.1254